Close this search box.

What are M367 Pills?

picture of Joe Gilmore
Medically Reviewed By: Diana Vo, LMFT

December 7, 2023

Table of Contents

M367 pills are often prescribed to manage moderate to severe pain stemming from injuries or specific medical conditions like arthritis. However, their potent pain-relief capabilities are accompanied by a heightened risk of misuse, meaning that the pills are stringently regulated by bodies like the FDA and DEA.

Understanding the basics of the M367 pill and its impact on the body can help anyone who may require this medication or who already uses it. Equipped with this knowledge, individuals can be prepared to respond appropriately if someone they care about develops a dependence on this drug.

heart icon that is 2 hands holding

Need help getting addiction treatment?

  • What pill is M367?
  • What are M367 prescribed for?
  • Can you OD on hydrocodone?
  • How to connect with hydrocodone addiction treatment in Southern California.

So what are M367 pills?

What Kind of Pill is M367?

M367 is a prescription medication that typically comes in pill form. It is a combination drug that contains two active ingredients: hydrocodone bitartrate and acetaminophen. Hydrocodone is an opioid (narcotic) painkiller, while acetaminophen is a non-narcotic painkiller and fever reducer.

M367 pills are also known as:

  • White pill M367
  • Hydrocodone M367

M367 is a white capsule-shaped pill with a raised back ridge. Manufactured by Mallinckrodt Pharmaceuticals, it contains acetaminophen (325mg) and hydrocodone bitartrate (10mg). This medication is commonly prescribed to alleviate back pain and manage arthritis symptoms.

M367 pills are commonly used to manage moderate to severe pain caused by various conditions, injuries, or surgeries. They belong to the category of medications known as opioid analgesics and are available by prescription only. Take M367 pills exactly as prescribed by a healthcare provider and be aware of the potential risks and M367 side effects. M367 contains a relatively high dose of the opioid component, which can lead to side effects and should be used with caution under a healthcare provider’s guidance.

Hydrocodone Acetaminophen Addiction

Hydrocodone acetaminophen, often found in medications like M367, is an opioid combination known for its effectiveness in pain management. That said, its use carries the risk of developing tolerance, dependence, and, in some cases, addiction. Here’s a breakdown of these stages:

  • Tolerance: With prolonged use, the body can become tolerant to the effects of hydrocodone acetaminophen. This means that over time, you may require higher doses to achieve the same level of pain relief.
  • Dependence: Dependence occurs when the body becomes reliant on the presence of the drug to function normally. Stopping or reducing the medication may trigger the presentation of withdrawal symptoms like nausea, sweating, and restlessness.
  • Addiction: Addiction is characterized by a compulsive desire to use the medication, often driven by cravings and a loss of control over use, despite negative consequences. It can have profound effects on a person’s physical and mental health, as well as their daily life.

Use hydrocodone acetaminophen under a healthcare provider’s guidance and only as prescribed to minimize the risk of progressing from tolerance to dependence, and potentially addiction. If you suspect that you or someone you know is struggling with hydrocodone acetaminophen addiction, seeking professional help is essential for effective treatment and recovery.

A woman is resting her head on a table to representing hydrocodone m367 side effects

Hydrocodone M367 Side Effects

Hydrocodone M367, a medication prescribed to manage pain, can be associated with various side effects. While not everyone will experience these effects, it is beneficial to be aware of adverse reactions. Common side effects of hydrocodone M367 may include:

  • Drowsiness: Hydrocodone is known for its sedative properties, which can lead to drowsiness or sleepiness. It is advised not to operate heavy machinery or engage in activities requiring mental alertness while taking this medication.
  • Nausea and vomiting: Some people may experience nausea and vomiting when using hydrocodone M367. Taking the medication with food or as directed by a healthcare provider can help alleviate this side effect.
  • Constipation: Opioid medications like hydrocodone can result in constipation. Increasing fluid intake and dietary fiber may help ease this issue.
  • Dizziness: Dizziness or lightheadedness can occur, particularly when changing positions rapidly. Caution is advised when standing up from a sitting or lying position.
  • Dry mouth: Hydrocodone can cause a dry mouth sensation. Staying well-hydrated and using sugar-free candies or gum may provide relief.
  • Itching: Some individuals may experience itching or skin rash as a side effect of hydrocodone M367.
  • Confusion: In certain cases, hydrocodone can lead to confusion or impaired cognitive function.
  • Respiratory depression: Although rare, hydrocodone can slow down breathing in some individuals, potentially leading to respiratory depression. Seek immediate medical attention if you experience shallow or slowed breathing.

Report any severe or persistent side effects to your healthcare provider promptly. Additionally, take hydrocodone M367 exactly as prescribed to minimize the risk of side effects and closely monitor your response to the medication. Always consult with a healthcare professional for guidance on managing these side effects and any concerns related to hydrocodone M367 use.

Hydrocodone Overdose

Hydrocodone bitartrate and other opioids can lead to overdose if consumed in excessive amounts, and acetaminophen and hydrocodone can pose significant dangers when taken in large doses. When these drugs are combined, it can result in a polydrug overdose. The signs and symptoms of an overdose can vary based on individual factors such as body chemistry, weight, prior exposure to narcotic drugs, and the dose ingested.

Overdose hydrocodone

According to medical literature, a lethal overdose of hydrocodone typically occurs around the 90mg threshold. Near this point, individuals may experience severe symptoms requiring immediate medical attention, including:

  • Extremely pale complexion and clammy skin
  • Unresponsiveness
  • Dangerously low heart rate, often less than 50 beats per minute
  • Unconsciousness, rendering the person unresponsive
  • Impaired speech or slurred speech
  • Constricted pupils, commonly referred to as pinpoint pupils
  • Vomiting or making gurgling sounds with saliva bubbling around the mouth

The most critical consequences of a hydrocodone overdose are related to dose-dependent respiratory and cardiovascular depression. Since the drug impacts involuntary bodily functions, it can slow down the respiratory rate, hindering sufficient respiration and oxygen exchange. This oxygen deficiency can lead to brain, heart, and organ damage, potentially resulting in brain death. Immediate medical intervention is imperative to prevent overdose or fatality.

Acetaminophen overdose

While the likelihood of overdosing on acetaminophen tablets taken as prescribed is low, the risk increases when acetaminophen is part of an M367 tablet, where it is present in higher concentrations. Accidental ingestion of a significant amount of acetaminophen before reaching the desired hydrocodone dosage can occur. Common symptoms of acetaminophen overdose include:

  • Weakness
  • Mental confusion
  • Abdominal pain
  • Decreased appetite
  • Nausea and vomiting
  • Jaundice (yellowing of the skin and eyes)

The most concerning consequence of acetaminophen overdose is potentially fatal hepatic necrosis, where excessive acetaminophen causes severe liver damage, leading to organ failure. Signs of hepatic necrosis may manifest as sudden onset nausea, abdominal pain, and weakness.

Given that M367 is a combination of hydrocodone and acetaminophen, the symptoms of an overdose can occur simultaneously when consumed excessively. Immediate medical attention is crucial when an overdose is suspected to mitigate its potentially dire consequences.

Treatment for M


What is a pain pill with M367 on it?

M367 pill is a combination medication that contains hydrocodone and acetaminophen. It is commonly prescribed to manage moderate to severe pain.

What is the difference between oxycodone and hydrocodone?

The primary difference between oxycodone and hydrocodone lies in their chemical structure and strength. Oxycodone is generally considered more potent than hydrocodone, making it effective for severe pain management. Both are opioids, but oxycodone is often prescribed when hydrocodone does not provide adequate pain relief.

What is the highest amount of hydrocodone?

The highest amount of hydrocodone typically available in prescription medications is 10mg, often combined with acetaminophen in formulations like Vicodin (hydrocodone/acetaminophen 10/325) or Norco (hydrocodone/acetaminophen 10/325). However, doses exceeding this amount should only be administered under careful medical supervision due to the increased risk of side effects and dependence.

What is the white pill with M367 on one side?

An M367 white tablet is a hydrocodone-acetaminophen opioid drug used in medical settings to treat pain after a surgical procedure. Some individuals can become addicted to the drug when used outside of medical supervision.

an image of the Renaissance Recovery logo representing hydrocodone addiction rehab

Get Treatment for M367 Addiction at Renaissance Recovery

If you have developed an addiction to prescription drugs, we can help you initiate a sustained recovery at Renaissance Recovery in Southern California. For those who require the most flexible and affordable pathway to sobriety, we specialize in treating addictions in an outpatient setting, allowing you to remain anchored to your everyday commitments.

Choose the level of structure and support and structure you need from these programs:

All treatment programs at our luxury beachside facility provide personalized therapy that combines the following interventions:

When you are ready to move beyond addiction to M367 pills, call admissions at 866.330.9449.



At Renaissance Recovery our goal is to provide evidence-based treatment to as many individuals as possible. Give us a call today to verify your insurance coverage or to learn more about paying for addiction treatment.

Close this search box.

Joseph Gilmore has been in the addiction industry for three years with experience working for facilities all across the country. Connect with Joe on LinkedIn.

Text a Recovery Expert

Text our team to get the help you need ASAP.

Use Our 24 Hour text line. You can ask questions about our program, the admissions process, and more.