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Oxycodone and Your Brain: Can It Heal?

Oxycodone, also referred to as OxyContin, is an opiate and as such, the effects of continued use or abuse have been studied extensively. One of the greatest areas of study has centered around the impact of oxycodone on the brain. There are many effects of oxycodone, both short and long term that require prescription drug addiction treatment.

What Is Oxycodone?

Oxycodone, brand name OxyContin, is a prescription medication often dispensed to help manage pain. This opiate is one of the most commonly abused drugs that lead to addiction. Like all opiates, it has a powerful effect on the brain, even from the first dose. Scientists have long studied these effects in a range of patients. The data they’ve collected has had been nothing short of amazing but at the same time, quite concerning.

Examining the Impact of Oxycodone on the Brain

Opiates work by attaching themselves to the many opioid receptors within one’s body. Our bodies have naturally occurring opioids which help calm us down because they manage the pleasure and reward systems within our brains.

With synthetic opioids like oxycodone, your reward system is greeted with a rush of dopamine, which serves as a powerful neurotransmitter. Dopamine signals the neurons of your body in such a manner that it creates a much higher level of excitement, pleasure, or euphoria. The heart rate becomes more rapid, senses are more acute and the body is in a state of excitement. This is often referred to as a “high.”

As you might have guessed, the body and brain like this sensation and users will be compelled to seek it again and again. This is the basis of addiction. Our brains naturally seek out these rushes, whether initiated by adrenaline or through the ingestion of stimulants or narcotics. The body knows only that it craves and needs these ongoing feelings of pleasure. Even in the absence of opiates, our brains seek reward or pleasure from activities like eating or sex.

Increased Tolerance to OxyContin

The chemical rewards triggered by any of these actions produce the dopamine that satisfies the brain. As time goes on, your brain and body crave it more and more. The problem with this is that after time, the rush diminishes significantly and might even disappear altogether. Continued use or abuse of opiates makes the receptors in the brain less sensitive to them over time. For the brain and body, this means that higher doses are needed to get the same high. You can see how this leads to increased tolerance and dependence on oxycodone.

Speaking medically, we know that the mesolimbic reward system in the brain and is responsible for dopamine and related feelings of pleasure. Because opiates and opioids provide direct rewards to this system, the brain naturally views the use of drugs positively insofar as it satisfies the brain’s reward system.

Effects of OxyContin on the Brain

Changes in the reward system of the brain is a big part of the reason why addiction is considered a disease — because abuse is directly linked to physical changes in the brain. While there are many individual factors that are relevant to how a person might develop an addiction to opiates or opioids, addiction is a real possibility if not carefully monitored. Scientists have looked at these factors to try to determine how fast it would take for an addiction to occur. What they found is that it depends on many factors, and without care and supervision, it is something that should not be ignored. Addiction can occur in just a few weeks, as demonstrated by studies.

These same studies showed that even after just a month of using morphine, users had undergone changes in their brains. MRIs of subjects showed that patients who took morphine had a reduction in their gray matter volume. This was true throughout the study. These reductions were largely in the areas of the brain that are in charge of the regulation of pain, cravings/urges, and emotions. The same studies showed increases in gray matter in the areas relating to learning and memory. This discovery lead scientists to conclude that opiates affect learning long-term behavior patterns, even after the pleasurable effects of using opiates have subsided.

Oxycodone and the Central Nervous System

One of the more dangerous side effects of how opiates affect the brain is how they slow the central nervous system. This leads to depressed respiration and is a big reason why people on opiates are at a high risk of an overdose. When this happens, a person’s breathing slows down significantly, and in extreme cases, it could stop completely. Obviously, this is a life-threatening condition.

Can You Heal After Oxycodone (OxyContin) Abuse?

Opiates affect the brain in so many ways, the damage can take months or even years to reverse. Opiates might produce a quick high, but users are playing with fire. They seem especially malicious in how they affect users. They attach themselves to just the right receptors in the brain to make them hard to resist. Users quickly become addicted and crave higher and higher doses.

Long term use or abuse can have serious, long-lasting side effects. Even after someone stops using opiates, their brain will continue to display evidence of the effects of the drugs. It takes a long time to recover with post-acute withdrawal symptoms that might include a myriad of symptoms.

Some of those include:

  • Apathy
  • Mood swings
  • Anxiety
  • Problems concentrating
  • Memory loss
  • Sleeplessness or insomnia

Recovery from opioid use or prescription medications like oxycodone requires professional supervision and medical monitoring.

OxyContin Rehab

 If you or a loved one is struggling with an OxyContin addiction there are oxycodone treatment centers in California and around the country that can help you conquer this addiction and achieve long-term sobriety. 

During your stay at an OxyContin drug rehab, clients will be exposed to multiple different types of treatment and therapies to help them learn more about their addiction and develop the tools and strategies that they need to overcome these issues. Some common forms of therapy that you will likely go through include cognitive behavioral therapy, dialectical behavioral therapy, holistic therapy programs, and more.
 

Oxycodone Addiction Treatment

It’s for so many side effects that patients seeking recovery typically start with drug detox and rehab programs to get them off the drugs. Afterward, there is a follow up with intensive outpatient (IOP) or outpatient treatment to slowly adapt to a life without drugs.

The following are some of the levels of care to help those suffering from oxycodone drug abuse and are looking for an oxy rehab:


Renaissance Recovery is an Orange County drug rehab center, we focus on addiction treatment through the mind, body, and spirit. If you or a loved one is suffering from addiction, Renaissance Recovery can help recommend a program to fit your needs. Many rehab programs and oxycodone treatment centers are covered by private insurance or for those who can’t afford insurance, Medicare or Medicaid may be available.

Contact Renaissance Recovery today by calling 866-330-9449 to speak with addiction specialists about oxycodone addiction treatment programs in CA.

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Renaissance Recovery Coronavirus Policy Update

As the national pandemic continues to make it increasingly difficult for individuals to receive quality aftercare, The District Recovery Community & Renaissance Recovery has provided a solution to all those seeking long term care. We are proud to announce that we will be offering all aspects of our treatment including intimate groups, one on one therapy, and case management to individuals in all states from the comfort and safety of your home. This is a great option for clients that are in need of continued treatment, but are returning home to be with their families during this time.

The District Recovery Community and Renaissance Recovery will remain in operation during this time and continue to serve our mission of treating those suffering from alcoholism and addiction.

We encourage you all to reach out to learn more about how we can work together to ensure that our clients remain sober, safe, and continue to get the help that they need.