Damason-P Withdrawal: Quitting, Symptoms, Timeline, & Help

Updated January 17, 2026

Written By:

Dr. Matt A. D’Urso
LMHC, LPCC

Content Manager:

Amy Leifeste

Editor:

Karena Mathis

Written By:

Dr. Matthew A. D’Urso LMHC, LPCC

Content Manager:

Amy Leifeste

Editor:

Karena Mathis

Table of Contents

Damason-P is a prescription pain medication that combines hydrocodone, a potent opioid, with aspirin to provide relief from moderate to severe pain. While effective for managing pain, Damason-P carries a significant risk of addiction due to its opioid component. Over time, misuse or prolonged use can lead to physical dependence, making it difficult to stop taking without experiencing withdrawal symptoms.

This guide outlines what to expect from the withdrawal process and how to connect with compassionate and effective treatment for opioid addiction.

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Drug Classifications

Damason-P pairs hydrocodone, a semi-synthetic opioid, with aspirin, an NSAID (non-steroidal anti-inflammatory drug). Aspirin reduces inflammation, fever, and pain, while hydrocodone interacts with opioid receptors in the brain to block pain signals and induce a sense of calm.

Hydrocodone is a Schedule II controlled substance under the Controlled Substances Act, meaning it has recognized medical use but a high potential for abuse and addiction. Aspirin is an over-the-counter salicylate drug used for pain relief and heart health.

Damason-P is also classified by the FDA as a Category C pregnancy drug, meaning it may pose risks to unborn babies and can pass into breast milk. Nursing infants may experience drug dependence or withdrawal symptoms. Due to these classifications, Damason-P should only be used under a doctor’s supervision.

Effects and Symptoms of Abuse

Hydrocodone in Damason-P makes it highly addictive. Misuse can involve taking higher doses than prescribed, using it more frequently, or combining it with other substances to enhance effects, potentially leading to addiction.

Misusing Damason-P may cause:

  • Euphoria or a sense of extreme well-being
  • Drowsiness or sedation
  • Slurred speech or slowed reflexes
  • Difficulty concentrating
  • Constipation or gastrointestinal discomfort

Over time, consistent misuse can result in:

  • Physical dependence: The body begins to rely on the drug to function normally.
  • Tolerance: Higher amounts are needed to achieve the same effects.
  • Health complications: Liver damage from aspirin or respiratory issues from hydrocodone.
  • Mental health challenges: Anxiety, depression, or emotional instability.

Behavioral signs to watch for include:

  • Obsessive thinking about the next dose or obtaining more medication
  • Doctor shopping to obtain additional prescriptions
  • Neglecting responsibilities at work, school, or home
  • Withdrawing from family, friends, or social activities
  • Risk-taking behaviors, such as driving under the influence or mixing with alcohol

Many begin misusing Damason-P unintentionally through chronic pain management. Others may use it to escape emotional stress. Early intervention can prevent worsening addiction and open the door to recovery.

Signs of a Damason-P Addiction

Addiction develops gradually, starting with misuse and progressing into dependence. Recognizing physical, psychological, and behavioral signs early can lead to effective intervention.

Physical signs include:

  • Withdrawal symptoms: Flu-like symptoms such as nausea, sweating, and body aches when not using the drug.
  • Increased tolerance: Needing higher doses to achieve the same effects.
  • Chronic fatigue: Feeling constantly tired or lethargic.
  • Gastrointestinal issues: Persistent constipation or abdominal pain.

Behavioral changes may include:

  • Secretive behavior: Hiding medication use or lying about dosage.
  • Neglect of responsibilities: Falling behind at work, school, or home.
  • Social withdrawal: Pulling away from friends, family, and activities.

Mental effects of addiction may include:

  • Obsessive thoughts: Constantly thinking about the next dose or running out of medication.
  • Mood swings: Irritability, depression, or anxiety between doses.
  • Emotional detachment: Feeling disconnected from loved ones or daily life.

Identifying these signs early can make a significant difference. With proper help, individuals can overcome addiction and reclaim their lives.

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Detoxification and Withdrawal

Recovering from Damason-P addiction begins with detoxification, the process of clearing the drug from the body. While essential for recovery, detox can be challenging. Withdrawal symptoms can be intense and typically require medical supervision.

When someone stops using Damason-P, their body adjusts to the absence of the drug, triggering withdrawal as the brain and nervous system attempt to regain balance.

Common Damason-P withdrawal symptoms include:

  • Muscle pain and body aches
  • Nausea, vomiting, and diarrhea
  • Insomnia or disrupted sleep patterns
  • Sweating and chills
  • Intense cravings for the drug

Symptoms typically begin within 24 to 48 hours after the last dose, peak around 72 hours, and gradually subside over one to two weeks. Psychological symptoms, such as anxiety and depression, may persist longer.

There are two primary approaches to Damason-P detox:

  • Inpatient detox: Individuals stay at a treatment facility with 24/7 medical care. Ideal for severe addictions or those lacking a supportive home environment.
  • Outpatient detox: People live at home but attend regular medical appointments to monitor progress. Provides flexibility but requires a strong support system.

Medications may be prescribed to ease withdrawal and reduce cravings, including:

  • Buprenorphine: Helps manage opioid withdrawal symptoms.
  • Clonidine: Reduces anxiety, sweating, and muscle pain.
  • Anti-nausea medications: Address gastrointestinal discomfort.

Attempting detox without medical supervision can be dangerous, leading to complications such as severe dehydration or relapse. A structured detox program provides medical care, emotional support, and a clear path to long-term recovery.

Signs of a Damason-P Overdose

An overdose can occur when someone takes too much Damason-P or combines it with other substances like alcohol or sedatives. Overdoses are medical emergencies requiring immediate attention.

Common signs include:

  • Extreme drowsiness: Difficulty staying awake or sudden loss of consciousness.
  • Respiratory depression: Slow, shallow, or irregular breathing.
  • Blue lips or fingertips: Sign of oxygen deprivation.
  • Severe stomach pain: Often accompanied by nausea or vomiting.
  • Confusion or delirium: Disorientation or inability to focus.

Factors that increase overdose risk:

  • Taking higher doses than prescribed
  • Combining Damason-P with other CNS depressants
  • Misjudging tolerance after a period of abstinence

If you suspect an overdose:

  • Call 911 immediately
  • Administer Narcan (naloxone) if available
  • Stay with the individual, keep them awake, and monitor breathing

Prevent overdose by using Damason-P only as prescribed and avoiding other substances. Seeking professional treatment can help prevent overdose and support lasting recovery.

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If you need help for yourself or a loved one battling opioid addiction, contact Renaissance Recovery. We can connect you with detox centers and ongoing treatment at our Florida or California rehabs. Our outpatient programs allow you to live at home while attending weekday therapy sessions.

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Sources

  1. https://medlineplus.gov/genetics/gene/oprm1/
  2. https://www.deadiversion.usdoj.gov/schedules/schedules.html
  3. https://www.ncbi.nlm.nih.gov/books/NBK507858/
  4. https://pmc.ncbi.nlm.nih.gov/articles/PMC3552465/
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