Xanax Withdrawal Symptoms, Timeline & Detox Treatment

Xanax (alprazolam) is a widely prescribed medication that helps people manage anxiety and panic disorders. While it’s effective when taken as directed, Xanax can also be highly addictive. Over time, even those who take it as prescribed may develop physical dependence, making it challenging to stop without experiencing uncomfortable and potentially dangerous withdrawal symptoms. 

While the journey to overcome Xanax dependence can be tricky, it’s also one of the most fundamental steps toward regaining control of your life. Xanax withdrawal symptoms, ranging from anxiety and insomnia to more severe effects like seizures, can make this process intimidating. That said, becoming aware of what to expect during alprazolam withdrawal can ease some of the fear and uncertainty.

This guide to Xanax detox explores all aspects of alprazolam withdrawal, from the most common signs and symptoms to the timeline and treatment. You will also learn how to detox from Xanax safely and comfortably.

What Is Xanax (Alprazolam)?

Xanax (alprazolam) is a prescription medication commonly used to treat anxiety and panic disorders. It belongs to a group of drugs called benzodiazepines, which work by calming the CNS (central nervous system). By increasing the effects of a natural brain chemical called GABA (gamma-aminobutyric acid), Xanax helps reduce feelings of anxiety and promotes relaxation [1].

Doctors typically prescribe Xanax for short-term use because of its effectiveness in relieving symptoms quickly. That said, benzos can lead to dependence if used over an extended period, even when taken as directed. Its short-acting nature means the drug works fast, but it also leaves the body quickly, which can provoke a cycle of repeated use to avoid benzo withdrawal symptoms.

Xanax is a Schedule IV controlled substance, meaning it has medical value but carries a risk of misuse and addiction [2].

How Addictive is Xanax?

Xanax has a high potential for addiction, even when taken as prescribed. This is partly due to how it interacts with the brain’s reward system. The calming effect it produces can become habit-forming, particularly for individuals with underlying stress, anxiety, or other mental health conditions.

People who misuse Xanax may take higher doses or use it more frequently than prescribed, seeking the euphoric or sedative effects. Misuse can rapidly lead to tolerance, where the body requires more of the drug to achieve the initial effects. This can escalate into physical and psychological dependence over time. 

Research shows that individuals with a history of substance use disorders are at a higher risk of developing dependence on Xanax [3]. Additionally, combining Xanax with alcohol or other substances significantly increases the likelihood of addiction and dangerous side effects.

Xanax Withdrawal

Alprazolam withdrawal occurs when someone stops taking Xanax after their body has become dependent on it. Dependence means the body has adapted to the drug’s presence, altering its natural production of calming chemicals like GABA. When Xanax is suddenly removed, the brain struggles to restore balance, triggering withdrawal symptoms.

Alprazolam withdrawal is not just physical but also involves psychological side effects. Many people feel a resurgence of the anxiety or panic they initially sought to manage, often in a more intense form. This rebound effect can make the withdrawal process feel overwhelming.

Withdrawal can be divided into acute and protracted phases. The acute phase includes the most severe symptoms, while the protracted phase involves lingering effects that may last weeks or months.

Xanax Withdrawal Symptoms

Withdrawal from Xanax can produce a wide range of symptoms that vary in intensity depending on the person.

The most frequently reported symptoms of alprazolam withdrawal include:

• Anxiety and panic attacks: A sudden increase in anxiety, often more severe than the anxiety the medication was initially prescribed to treat.
• Insomnia and restlessness: Difficulty falling or staying asleep, accompanied by feelings of agitation and unease.
• Muscle pain and stiffness: Aching muscles, cramps, and general physical discomfort.
• Nausea, vomiting, and loss of appetite: Gastrointestinal distress is common as the body adjusts to the absence of the drug.
• Sweating and rapid heartbeat: These symptoms, caused by an overactive nervous system, can leave individuals exhausted and overwhelmed.
• Tremors and uncontrollable shaking: Shaking hands or involuntary movements are hallmark signs of alprazolam withdrawal, especially in more severe cases.

Alongside these physical effects, many people experience significant psychological distress during Xanax withdrawal, including:

• Mood swings: Irritability, anger, and frustration can appear without warning, making it challenging to manage daily interactions.
• Depression: Feelings of sadness, hopelessness, and despair often accompany withdrawal, particularly in individuals with pre-existing mental health conditions.
• Cognitive difficulties: Difficulty concentrating, forgetfulness, and confusion are common as the brain adapts to functioning without Xanax.

In some cases, alprazolam withdrawal can lead to severe and potentially life-threatening symptoms, such as:

• Seizures: These can occur without warning and require immediate medical attention. Seizures are more likely in people who stop taking Xanax abruptly or use high doses of this benzo.
• Hallucinations and delusions: Some individuals experience sensory distortions or false beliefs, which can be frightening and disorienting.
• Delirium: A state of severe confusion and agitation, often accompanied by a loss of awareness of surroundings.

In some cases, symptoms of alprazolam withdrawal can persist for weeks or months after discontinuation. This condition—PAWS or post-acute withdrawal syndrome—may include:

• Persistent depression or anxiety.
• Insomnia that lasts beyond acute withdrawal.
• Difficulty managing stress or emotional triggers. 

How Long Does Xanax Withdrawal Last?

The benzo withdrawal timeline varies from person to person, although it usually unfolds as follows:

• 6 to 12 hours after the last dose: Early symptoms, such as anxiety and irritability, begin to appear.
• 2 to 4 days: Symptoms peak, with severe anxiety, tremors, and nausea being common.
• 5 to 14 days: Physical symptoms start to subside, but emotional challenges may persist.
• Weeks to months: Some people find that cravings and insomnia may linger during the protracted phase of alprazolam withdrawal.

Each person’s experience is unique, and medical supervision can help tailor a withdrawal plan to individual needs.

Xanax Withdrawal Timeline

Alprazolam withdrawal occurs in the following distinct phases:

• Early phase: Mild symptoms, such as restlessness and irritability, emerge within hours of the last dose
• Peak phase: Symptoms intensify, often including severe anxiety, nausea, and hallucinations. This phase usually lasts 2 to 4 days.
• Subacute phase: Physical symptoms begin to fade, but emotional challenges like depression or PAWS may persist.
• Long-term effects: For some, protracted symptoms require continued treatment and support.

Factors that Affect Xanax Withdrawal

Not everyone experiences alprazolam withdrawal in the same way. The following factors can influence the severity and duration of symptoms:

• Dosage and duration of use: Higher doses or prolonged use lead to more intense symptoms.
• Concurrent substance use: Combining Xanax with alcohol or opioids complicates withdrawal.
• Mental health conditions: Pre-existing anxiety or depression can inflame symptoms of alprazolam withdrawal.
• Genetics and metabolism: Individual differences affect how quickly the drug is processed.

How Much Xanax Causes Withdrawal?

Dependence can develop even at therapeutic doses if Xanax is used for an extended period. However, higher doses and prolonged use significantly increase the risk of withdrawal. Individuals taking more than 4mg daily or using the drug for several months are at heightened risk.

Even people using lower doses may experience withdrawal if they stop abruptly. The alprazolam withdrawal process can be streamlined with close medical supervision.

Is it Safe to Detox from Xanax Naturally or at Home?

Detoxing from Xanax naturally or at home without medical supervision is not recommended and can be extremely dangerous [4]. Xanax is a potent benzodiazepine that alters the brain’s chemistry, and stopping it abruptly can lead to severe physical and psychological symptoms.

Dangers of Xanax detox at home include: 

• Severe withdrawal symptoms: Xanax withdrawal symptoms can range from mild to life-threatening. While some individuals may experience anxiety, insomnia, or nausea, others could face seizures, hallucinations, or delirium. Seizures are one of the most significant risks of unsupervised withdrawal and can occur unexpectedly, leading to serious complications such as injury or even death.
• Rebound effects: Many people experience rebound anxiety or panic, where the symptoms Xanax was initially prescribed to treat return more intensely. Without proper management, these feelings can be overwhelming and may lead individuals to relapse in an attempt to find relief.
• Emotional distress: Psychological symptoms, including depression, irritability, and mood swings, can make the withdrawal process emotionally taxing. These symptoms often require professional support.
• Risk of relapse: The discomfort of withdrawal can push individuals to return to Xanax use, often in higher doses than before. This cycle increases the risk of overdose, particularly if other substances like alcohol are involved. 

Why Professional Detox is Safer

In a medical detox setting, healthcare professionals monitor patients 24/7 to manage withdrawal symptoms and prevent complications. They can respond quickly to emergencies, such as seizures, and adjust treatment plans to ensure safety and comfort. Doctors may prescribe medications to ease withdrawal symptoms – more on this directly below. These medications can make the detox process significantly more tolerable and safer than attempting to quit on your own.

A supervised tapering schedule involves gradually reducing the Xanax dosage over time, allowing the brain and body to adjust slowly [5]. This approach minimizes withdrawal symptoms and significantly reduces the risk of severe complications.

Professional detox programs often include counseling or therapy to help individuals cope with the emotional aspects of withdrawal. This support can be critical in building resilience and preparing for long-term recovery.

Medications Used to Treat Xanax Withdrawal Symptoms

Certain medications can ease the symptoms of Xanax withdrawal and reduce the risk of severe complications. Common options include:

• Long-acting benzodiazepines: Medications like diazepam or clonazepam stabilize symptoms during tapering.
• Anticonvulsants: Reduce the risk of seizures.
• Beta-blockers: Help manage physical symptoms like rapid heartbeat or high blood pressure.
• Antidepressants: Address underlying mood disorders or withdrawal-related depression.

In addition to medications, behavioral therapies, and support groups can help address the emotional challenges of withdrawal and build long-term resilience.

Alprazolam Withdrawal FAQs

How to cope with Xanax withdrawal?

Coping with Xanax withdrawals involves seeking medical supervision, building a support system, and practicing self-care. Gradual tapering under a doctor’s guidance can minimize symptoms of Xanax withdrawal, while relaxation techniques and a healthy lifestyle aid recovery. Surrounding yourself with supportive people or joining a support group can make the process less overwhelming.

What medication is used for Xanax withdrawal?

Medications like long-acting benzos (diazepam), anticonvulsants (gabapentin), and beta-blockers are often used to manage alprazolam withdrawal symptoms. These treatments help stabilize the body and reduce risks such as seizures or severe anxiety. Antidepressants may also be prescribed to address mood disturbances.

How long after stopping Xanax can you have a seizure?

The highest risk of seizures occurs within 6 to 48 hours after the last dose of Xanax as the brain adjusts to the absence of the drug. This risk is most significant for individuals who stop abruptly or have a history of high-dose use. Medical supervision is essential during this period to prevent complications.

What is one of the first signs of withdrawal?

Rebound anxiety is one of the first signs of alprazolam withdrawal, where symptoms like restlessness and increased nervousness appear within hours of the last dose. Other early symptoms include insomnia and irritability. These initial signs indicate the brain’s struggle to adapt without the medication.

Get Treatment for Withdrawal from Xanax at Renaissance Recovery

If you or someone you love needs help with Xanax withdrawals, reach out to Renaissance Recovery. We can connect you with licensed medical detox centers near you so you can kickstart the recovery process.

After you detox from Xanax, you can move into ongoing outpatient treatment at one of our rehabs by the beach in California or Florida. This allows you to live at home while meeting your everyday commitments and attending weekday therapy sessions to combat addiction to benzos.

All benzo addictions are unique, so all our treatment plans are personalized to reflect this. Therapies may include: 

• Medication management
• Counseling
• Motivational therapies
• Talk therapies
• Group therapy
• Family therapy
• Holistic treatments
• Aftercare planning

When you’re ready to move beyond alprazolam withdrawal, call 866-330-9449

Sources

[1] https://pmc.ncbi.nlm.nih.gov/articles/PMC3684331/

[2] https://www.deadiversion.usdoj.gov/schedules/schedules.html

[3] https://pmc.ncbi.nlm.nih.gov/articles/PMC5846112/

[4] https://pmc.ncbi.nlm.nih.gov/articles/PMC5846112/

[5] https://www.oregon.gov/oha/HPA/DSI-Pharmacy/MHCAGDocs/Tapering-Benzodiazepines.pdf